RPG environment (POLL)

So you have chosen. The next real game that I’m going to program from the ground up, based on APOCALYX, is a Role-Playing Game. In fact, the results are: RPG (30), RTS (12), FPS (6), Other (0). Now it's the time to choose the background of the game. There are so many possibilities that I'm disoriented: Is it better to choose the usual inflated medieval asset, or a more original one? The choice is up to you.
Here I simply list several possibilities, with just a few ideas about the possible careers, but you can also propose something different. In the last case choose "Other" and send an email describing your idea: the more original, the better. You can also offer your help, if you want: in that case contact me!

• Galactic Empire to boldly go where no one has gone before
• Post-atomic Mad Max-like earth or Waterworld-like oceans
• Gangsters from news-boy to gang boss or police chief
• Western Fronteer gold-miner, bounty-killer, cow-boy, gambler
• Buccanneers from ship-boy to governor or captain of galleons
• Ancient Japan ronin, samurai, ninja, shogun, emperor
• Middle Earth-like goblins, trolls, orcs, elves, dwarves, humans
• Arthurian cycle from esquire to king Arthur or wizard Merlin
• Roman Empire from slave to gladiator; from private to emperor
• Ancient Egypt from slave to Pharaoh or Minister of religion
• Other give your fantasy a chance: describe your ideas